In 1967, the World Meteorological Organisation and the International Council of Scientific Unions launched the Global Atmospheric Research Program (GARP), which lasted until 1982. The primary goals of the programme were international cooperation in global atmospheric observation to improve weather forecasting and to study climatic changes. This article examines the development phase of GARP from approximately 1961 to 1967, focusing on the US meteorologists Jule Charney and Thomas Malone and the Swedish meteorologist Bert Bolin, who contributed to its organization. It shows a variety of relationships between science and politics, beginning with President John F. Kennedy’s call for scientific cooperation to ease international political tensions, followed by the diverse efforts of Charney, Malone, Bolin and others to help secure political support, and finally the protracted negotiations within the International Council of Scientific Unions to shape and organize the Global Atmospheric Research Program.