Aelian and Porphyry claim that only the horns of a specific species of Scythian ass can contain the corrosive water of the Styx. They also state that Alexander the Great received one of these horns from a certain Sopater as a gift, on which he had an epigram engraved before dedicating it at Delphi. This article explores the connection between this story and the reports of Alexander’s alleged assassination by the Antipatrids. In these reports, the poison used is often said to be the water of the Styx, held in an equine hoof. The tale reported by Aelian and Porphyry can be interpreted as part of the propaganda war during the time of the Diadochi, specifically as a piece of counter-propaganda responding to the accusation of treason against Antipater and his family and aiming to exonerate them.