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Ternary complex structure of human HGPRTase, PRPP, Mg2+, and the inhibitor HPP reveals the involvement of the flexible loop in substrate binding

Published online by Cambridge University Press:  01 December 1999

GANESARATNAM K. BALENDIRAN ,
JOSÉ A. MOLINA ,
YIMING XU ,
JAN TORRES-MARTINEZ ,
ROBERT STEVENS ,
PAMELA J. FOCIA ,
ANN E. EAKIN ,
JAMES C. SACCHETTINI  and
SYDNEY P. CRAIG
GANESARATNAM K. BALENDIRAN
Affiliation:
Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas 77843-2128
JOSÉ A. MOLINA
Affiliation:
Department of Biochemistry, University of Puerto Rico–Medical Sciences Campus, San Juan, Puerto Rico 00936
YIMING XU
Affiliation:
Department of Biochemistry, Temple University School of Medicine, Philadelphia, Pennsylvania 19140
JAN TORRES-MARTINEZ
Affiliation:
Laboratory of Molecular Parasitology and Drug Design, School of Pharmacy, CB#7360, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599
ROBERT STEVENS
Affiliation:
Mass Spectrometry Facility, Section of Biochemical Genetics, Duke University Medical Center, Research Triangle Park, North Carolina 27709
PAMELA J. FOCIA
Affiliation:
Laboratory of Molecular Parasitology and Drug Design, School of Pharmacy, CB#7360, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599
ANN E. EAKIN
Affiliation:
Laboratory of Molecular Parasitology and Drug Design, School of Pharmacy, CB#7360, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599
JAMES C. SACCHETTINI
Affiliation:
Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas 77843-2128
SYDNEY P. CRAIG
Affiliation:
Laboratory of Molecular Parasitology and Drug Design, School of Pharmacy, CB#7360, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599
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Abstract

The PDB accession number for the structure published in the above referenced article (Volume 8, Number 5, 1999, pp. 1023–1031) is 1D6N. We regret the omission in the original article.

Information

Type
ERRATA
Information
Protein Science , Volume 8 , Issue 12 , December 1999 , pp. 2815
Copyright
© 2003 The Protein Society

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